Avaliação preliminar da actividade antimicrobiana de diferentes extractos de larvas de Hermetia illucens para aplicação como ingrediente cosmético
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2020
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materiais de origem natural. A biomassa das larvas de Hermetia illucens (Linnaeus) é uma fonte potencial de compostos
com aplicabilidade em cosméticos, devido ao seu alto teor em lípidos, proteínas e polissacáridos. Além disso, essas
larvas são conhecidas por terem um sistema imunológico bem desenvolvido, sobrevivendo a habitats em decomposição,
podendo ser induzidas a produzirem péptidos antimicrobianos (AMP's). Além disso, da fração lipídica é possível obter
elevadas concentrações de ácido láurico, conhecido também por ter propriedades antimicrobianas. Essas substâncias
podem ser sondadas como conservantes alternativos em cosméticos, uma vez que os consumidores costumam preocuparse
com a segurança de conservantes convencionais, como os parabenos. O presente estudo pretendeu fazer uma avaliação
preliminar da atividade antimicrobiana dos extratos brutos obtidos a partir de diferentes métodos e solventes de extração
contra quatro microrganismos (bactérias Gram-positivas e negativas e leveduras). Os extratos diluídos não demostraram
inibição relevante do crescimento dos microrganismos testados em comparação com os controlos positivos usados. Estão
previstos ensaios adicionais para avaliar a atividade antimicrobiana de compostos ou frações isoladas a partir dos extratos
brutos.
Palavras-chave: extratos de Hermetia illucens, bioativos, atividade antimicrobiana, ingredientes para produtos de saúde
The cosmetic industry is continually searching for innovative ingredients, and there is a current trend in sourcing materials of natural origin. The Hermetia illucens (Linnaeus) larvae biomass is a potential source of compounds with applicability in cosmetics due to its high lipid, protein, and polysaccharide content. High concentrations of lauric acid, also known for also having antimicrobial properties, may be obtained from the lipid fraction. Additionally, these larvae are known to have a well-developed immune system, surviving in decomposition habitats, and can be induced to produce antimicrobial peptides (AMP's). These substances could be probed as alternative preservatives in cosmetics, as consumers are often concerned with the safety of conventional preservatives, such as parabens. The present study conducted a preliminary assessment of the antimicrobial activity of the crude extracts obtained from different extraction methods and extraction solvents against four microorganisms (Gram-positive and negative bacteria and yeasts). The use of diluted extracts did not show relevant inhibition of the growth of the tested microorganisms compared to the positive controls. Further assays are foreseen to test the antimicrobial activity of compounds or fractions isolated from the crude extracts. Keywords: Hermetia illucens extracts, bioactives, antimicrobial activity, health products ingredients
The cosmetic industry is continually searching for innovative ingredients, and there is a current trend in sourcing materials of natural origin. The Hermetia illucens (Linnaeus) larvae biomass is a potential source of compounds with applicability in cosmetics due to its high lipid, protein, and polysaccharide content. High concentrations of lauric acid, also known for also having antimicrobial properties, may be obtained from the lipid fraction. Additionally, these larvae are known to have a well-developed immune system, surviving in decomposition habitats, and can be induced to produce antimicrobial peptides (AMP's). These substances could be probed as alternative preservatives in cosmetics, as consumers are often concerned with the safety of conventional preservatives, such as parabens. The present study conducted a preliminary assessment of the antimicrobial activity of the crude extracts obtained from different extraction methods and extraction solvents against four microorganisms (Gram-positive and negative bacteria and yeasts). The use of diluted extracts did not show relevant inhibition of the growth of the tested microorganisms compared to the positive controls. Further assays are foreseen to test the antimicrobial activity of compounds or fractions isolated from the crude extracts. Keywords: Hermetia illucens extracts, bioactives, antimicrobial activity, health products ingredients
Descrição
Biomedical and biopharmaceutical research : jornal de investigação biomédica e biofarmacêutica
Palavras-chave
MEDICINA, BIOFARMÁCIA, ANTIMICROBIANOS, PRODUTOS COSMÉTICOS, MEDICINE, BIOPHARMACEUTICS, ANTIMICROBIAL, COSMETICS