Uma nova associação de uso tópico contendo óxido de zinco e extractos de aloe vera e camomila - estudos de estabilidade e segurança
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2015
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Edições Universitárias Lusófonas
Resumo
Atualmente, os produtos naturais apresentam um enorme potencial para as indústrias farmacêuticas e cosméticas.
Os objetivos deste estudo foram a formulação e a caracterização de três cosméticos contendo produtos naturais.
As formulações foram: 1) emulsão óleo-em-água; 2) emulsão água-em-óleo e 3) solução de limpeza. O óxido de
zinco foi escolhido como ingrediente ativo devido às suas propriedades regenerativas e os extratos de aloe vera
e camomila devido às suas propriedades antissépticas, anti-inflamatórias e também regenerativas. Os parâmetros
avaliados foram as características organoléticas, pH, viscosidade e a eficácia in vitro contra bactérias e fungos
comuns em doenças de pele. Foram igualmente efetuados estudos preliminares e acelerados de estabilidade e
segurança. Todos os produtos demonstraram estabilidade, textura suave, eficácia contra bactérias e fungos e
segurança, justificando estudos adicionais. Os resultados obtidos sugerem que estes novos produtos poderão ser
uma fonte promissora de produtos naturais com propriedades calmante e regenerativa para a pele.
Currently, natural products show an enormous potential for pharmaceutical and cosmetic industries. The goals of this study were to formulate and to characterise a novel combination of natural products. Formulations were 1) an oil-in-water emulsion, 2) a water-in-oil emulsion and 3) a cleansing solution. Zinc oxide was chosen as an active ingredient due to its healing properties, and chamomile and aloe vera extracts were chosen due to their antiseptic, anti-inflammatory and tissue regenerating properties. Organoleptic characteristics, pH, viscosity and in vitro efficacy for the most common bacteria and yeast of human skin were evaluated. Preliminary and accelerated stability studies and safety tests were also performed. All optimized products were stable, smooth in texture, effective against bacteria and yeast, and safe, justifying further studies. Results suggest that these novel products might be a promising source of natural compounds with soothing and regenerative properties for skin care.
Currently, natural products show an enormous potential for pharmaceutical and cosmetic industries. The goals of this study were to formulate and to characterise a novel combination of natural products. Formulations were 1) an oil-in-water emulsion, 2) a water-in-oil emulsion and 3) a cleansing solution. Zinc oxide was chosen as an active ingredient due to its healing properties, and chamomile and aloe vera extracts were chosen due to their antiseptic, anti-inflammatory and tissue regenerating properties. Organoleptic characteristics, pH, viscosity and in vitro efficacy for the most common bacteria and yeast of human skin were evaluated. Preliminary and accelerated stability studies and safety tests were also performed. All optimized products were stable, smooth in texture, effective against bacteria and yeast, and safe, justifying further studies. Results suggest that these novel products might be a promising source of natural compounds with soothing and regenerative properties for skin care.
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CIÊNCIAS FARMACÊUTICAS, PHARMACEUTICAL SCIENCES, PLANTAS MEDICINAIS, MEDICINAL PLANTS, PRODUTOS COSMÉTICOS, MEDICINAL PLANTS, ESTUDOS DE CASO, CASE STUDIES