Neocarya macrophylla (Chrysobalanaceae) : Review of taxonomy, ethnobotany, phytochemistry and biological activities
Miniatura indisponível
Ficheiros
Data
2024
Título da revista
ISSN da revista
Título do Volume
Editora
Edições Universitárias Lusófonas
Resumo
Neocarya macrophylla é usada tradicionalmente para fins alimentares, medicinais, espirituais e industriais. Também é utilizada como sabão, corante, cola, forragem, repelente de térmitas, lenha e como material estrutural. Existem poucos estudos sobre o conteúdo físico-químico, nutricional, fitoquímico e atividades farmacológicas que validem os benefícios de N. macrophylla para a humanidade como alimento, em cosméticos e produtos farmacêuticos. Os principais constituintes bioativos identificados na planta até agora são esteróides e flavonóides (tais como estigmasterol, quercetina, catequina e os seus glicosídeos relacionados, assim como glucosaminas). Os extratos das plantas mostraram boas atividades antiveneno, antimicrobiana, analgésica, anti-inflamatória, antimicobacteriana, anti-helmíntica e antioxidante. Estudos de toxicidade aguda confirmaram que a planta é tóxica. São necessários mais estudos sobre a planta para explorar outras atividades biológicas, alegadas por curandeiros tradicionais, e também para isolar mais compostos bioativos. Além disto, a avaliação da segurança e da tolerabilidade de N. macrophylla deve ser efetuada devido à sua utilização generalizada.
The Neocarya macrophylla plant is used traditionally for food, medicinal, spiritual and industrial purposes. It is also used as a soap, dye, glue, fodder, termite repellent, firewood and for structural materials. Few studies on the physicochemical, nutritional content, phytochemical and pharmacological activities have validated the benefits of N. macrophylla to humanity as a food, in cosmetics or pharmaceutical products. The major bioactive constituents identified in the plant so far are steroids and flavonoids, such as, stigmasterol, quercetin, catechin and its related glycosides, as well as glucosamines. Extracts of the plant have shown good antivenom, antimicrobial, analgesic, anti-inflammatory, antimycobacterial, anthelmintic and antioxidant activities. Acute toxicity studies have confirmed the plant to be toxic. More studies on the plant are required in order to exploit other biological activities as claimed by traditional healers and also to isolate more bioactive compounds. In addition, the safety and tolerability assessment of N. macrophylla should be undertaken due to its widespread usage.
The Neocarya macrophylla plant is used traditionally for food, medicinal, spiritual and industrial purposes. It is also used as a soap, dye, glue, fodder, termite repellent, firewood and for structural materials. Few studies on the physicochemical, nutritional content, phytochemical and pharmacological activities have validated the benefits of N. macrophylla to humanity as a food, in cosmetics or pharmaceutical products. The major bioactive constituents identified in the plant so far are steroids and flavonoids, such as, stigmasterol, quercetin, catechin and its related glycosides, as well as glucosamines. Extracts of the plant have shown good antivenom, antimicrobial, analgesic, anti-inflammatory, antimycobacterial, anthelmintic and antioxidant activities. Acute toxicity studies have confirmed the plant to be toxic. More studies on the plant are required in order to exploit other biological activities as claimed by traditional healers and also to isolate more bioactive compounds. In addition, the safety and tolerability assessment of N. macrophylla should be undertaken due to its widespread usage.
Descrição
Publisher Copyright: © 2024 ALIES. All rights reserved.
Palavras-chave
PHARMACEUTICAL SCIENCES, PHARMACOLOGY, PHARMACEUTICAL CHEMISTRY, PHARMACEUTICAL PRODUCTS, PLANT CHEMISTRY, ANALGESICS, ANTIMICROBIAL, ANTIOXIDANTS, CIÊNCIAS FARMACÊUTICAS, FARMACOLOGIA, QUÍMICA FARMACÊUTICA, PRODUTOS FARMACÊUTICOS, FITOQUÍMICA, ANALGÉSICOS, ANTIMICROBIANOS, ANTIOXIDANTES
Citação
Yusuf, A J, Abdullahi, M I, Muhammad, A A, Ibrahim, K G, Wasagu, H A, Bräuning, F Z, Bangay, G & Rijo, P 2024, 'Neocarya macrophylla (Chrysobalanaceae) : Review of taxonomy, ethnobotany, phytochemistry and biological activities', Biomedical and biopharmaceutical research : jornal de investigação biomédica e biofarmacêutica, vol. 21, no. 1, pp. 87-108. https://doi.org/10.19277/bbr.21.1.331