Ingestão oral de peptídeos bioativos de colágeno na melhoria da pele e cabelo : estudos clínicos por medidas instrumentais
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Data
2022
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Resumo
O efeito do uso de peptídeos de colágeno em vários aspectos da fisiologia da pele e do cabelo é conhecido,
porém necessita de mais estudos. Dessa forma, o objetivo deste artigo foi avaliar as alterações clínicas na pele e
cabelos após 90 dias de tratamento com suplementação oral de 5g/dia de peptídeos de colágeno. Para isso, foram
inscritas 60 participantes saudáveis do sexo feminino, com idades entre 45 e 60 anos, com o objetivo principal
de avaliar o efeito da ingestão de uma suplementação à base de peptídeos de colágeno bioativos no microrrelevo
cutâneo, redução de rugas, espessura e ecogenicidade da derme, bem como nas propriedades mecânicas do cabelo
usando técnicas biofísicas e de imagem da pele. O presente estudo mostrou benefícios importantes em parâmetros
relevantes da pele, densidade da derme e resistência do cabelo. Em conclusão, a suplementação oral com peptídeos
de colágeno é importante não só para a melhora das condições da pele, mas também para o cuidado do cabelo,
uma vez que aumenta significativamente a resistência mecânica do cabelo. Além disso, considerando que processo
de envelhecimento afeta a resistência mecânica do cabelo devido ao afinamento da fibra capilar, o tratamento
proposto foi eficaz para cabelos envelhecidos.
Palavras-chave: Peptídeos de colágeno, envelhecimento da pele, técnicas de imagem da pele, propriedades mecânicas
do cabelo, estudo clínico
The effect of collagen peptides on various aspects of skin and hair physiology is known but needs further studies. Thus, the objective of this study was to evaluate the clinical changes in skin and hair after 90 days of treatment with oral supplementation of 5 g/day of collagen peptides. For this, 60 healthy female participants were enrolled, aged 45 to 60 years old, with the primary objective of evaluating the effect of the ingestion of a bioactive collagen peptidesbased supplementation in the cutaneous microrelief, reduction of wrinkles, thickness, and echogenicity of the dermis, as well as in the mechanical properties of the hair using biophysical and skin imaging techniques. The present study showed important benefits in relevant skin visual parameters, dermis density, and hair strength with the obtained data. In addition, considering that the aging process affects the hair's mechanical resistance due to hair fiber thinner, the proposed treatment was effective for aged hair. In conclusion, the collagen peptides oral supplementation is essential not only for improving skin conditions but also for hair care once it significantly increases the mechanical hair resistance evaluated by objective measurements. Keywords: Collagen peptides, skin aging, skin imaging techniques, hair mechanical properties, clinical study
The effect of collagen peptides on various aspects of skin and hair physiology is known but needs further studies. Thus, the objective of this study was to evaluate the clinical changes in skin and hair after 90 days of treatment with oral supplementation of 5 g/day of collagen peptides. For this, 60 healthy female participants were enrolled, aged 45 to 60 years old, with the primary objective of evaluating the effect of the ingestion of a bioactive collagen peptidesbased supplementation in the cutaneous microrelief, reduction of wrinkles, thickness, and echogenicity of the dermis, as well as in the mechanical properties of the hair using biophysical and skin imaging techniques. The present study showed important benefits in relevant skin visual parameters, dermis density, and hair strength with the obtained data. In addition, considering that the aging process affects the hair's mechanical resistance due to hair fiber thinner, the proposed treatment was effective for aged hair. In conclusion, the collagen peptides oral supplementation is essential not only for improving skin conditions but also for hair care once it significantly increases the mechanical hair resistance evaluated by objective measurements. Keywords: Collagen peptides, skin aging, skin imaging techniques, hair mechanical properties, clinical study
Descrição
Biomedical and biopharmaceutical research : jornal de investigação biomédica e biofarmacêutica
Palavras-chave
CIÊNCIAS FARMACÊUTICAS, ENVELHECIMENTO CUTÂNEO, DIAGNÓSTICO POR IMAGEM, PELE, CABELO, ESTUDOS CLÍNICOS, PHARMACEUTICAL SCIENCES, SKIN AGEING, DIAGNOSTIC IMAGING, SKIN, HAIR, CLINICAL STUDIES, COLLAGEN PEPTIDES, PEPTÍDEOS DE COLAGÉNIO