Doença renal policística autossômica dominante em pacientes em hemodiálise no sul do Brasil

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dc.contributor.authorAlves, Everton Fernando
dc.contributor.authorTsuneto, Luiza Tamie
dc.contributor.authorPelloso, Sandra Marisa
dc.contributor.authorTorres, Paulo Roberto Aranha
dc.contributor.authorOtto, Guido Luis Gomes
dc.contributor.authorSilva, Adaelson Alves
dc.contributor.authorObregon, José Miguel Viscarra
dc.contributor.authorSilva, Leticia Nicoletti
dc.contributor.authorCarvalho, Maria Dalva de Barros
dc.contributor.institutionEscola de Ciências e Tecnologias Saúde
dc.date.issued2014-03-10
dc.descriptionBrazilian Journal of Nephrology
dc.description.abstractIntroduction: Autosomal dominant polycystic kidney disease is the most common hereditary renal disease in humans. Objective: To examine the prevalence, clinical and laboratory characteristics of patients with polycystic kidneys and relate disease manifestations by gender. Methods: This was an observational and retrospective study. All the medical records of patients with polycystic kidneys who initiated hemodialysis between 1995 and 2012, in four centers that treat patients of the coverage area of the 15th regional health Paraná (Brazil), were analyzed. Results: The study included 48 patients with polycystic kidneys, the primary cause of stage 5 CKD. Disease prevalence was one in 10,912 people. The average age of dialysis initiation was 50.7 years and the follow-up time on dialysis until transplantation (36.5 months) was lower among men. Hypertension was the most frequent diagnosis in 73% of patients, predominantly in women (51.4%). The liver cyst was the most frequent extrarenal manifestations in men (60.0%). The death occurred in 10.4% of patients using hemodialysis, and 60% of men. The class of antihypertensive drug used was that acts on the renin-angiotensin system with higher frequency of use among women (53.3%). The post-dialysis urea was significantly higher in men. Conclusion: The prevalence of the disease is low among hemodialysis patients in southern Brazil. The differences observed between genders, with the exception of the post-dialysis urea, were not significant. The findings are different from those reported in North America and Europe.en
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dc.identifier.citationAlves , E F , Tsuneto , L T , Pelloso , S M , Torres , P R A , Otto , G L G , Silva , A A , Obregon , J M V , Silva , L N & Carvalho , M D D B 2014 , ' Doença renal policística autossômica dominante em pacientes em hemodiálise no sul do Brasil ' , Brazilian Journal of Nephrology . https://doi.org/10.5935/0101-2800.20140005
dc.identifier.doihttps://doi.org/10.5935/0101-2800.20140005
dc.identifier.issn0101-2800
dc.language.isopor
dc.peerreviewedno
dc.publisherSociedade Brasileira de Nefrologia
dc.relation.ispartofBrazilian Journal of Nephrology
dc.rightsopenAccess
dc.subjectDIÁLISE
dc.subjectEPIDEMIOLOGIA
dc.subjectINSUFICIÊNCIA RENAL
dc.subjectDOENÇAS RENAIS
dc.subjectDIALYSIS
dc.subjectEPIDEMIOLOGY
dc.subjectKIDNEY FAILURE
dc.subjectKIDNEY DISEASES
dc.titleDoença renal policística autossômica dominante em pacientes em hemodiálise no sul do Brasilpt
dc.titleAutosomal dominant polycystic kidney disease in hemodialysis patients in southern Brazilen
dc.typearticle

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