Human and Companion Animal Proteus mirabilis Sharing

Ver registo simples
dc.contributor.authorMarques, Cátia
dc.contributor.authorBelas, Adriana
dc.contributor.authorMenezes, Juliana
dc.contributor.authorda Silva, Joana Moreira
dc.contributor.authorCavaco-Silva, Patrícia
dc.contributor.authorTrigueiro, Graça
dc.contributor.authorGama, Luís T.
dc.contributor.authorPomba, Constança
dc.contributor.institutionI-MVET - Investigação Medicina Veterinária (CECAV)
dc.date.issued2022-03
dc.descriptionPublisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.abstractProteus mirabilis is an important pathogen that is associated with urinary tract infections. This study aims to determine the colonization and sharing of P. mirabilis between healthy companion animals and humans that are living together and to evaluate the clonal relatedness of the fecal and clinical stains. Eighteen households (24 humans, 18 dogs, 8 cats) with at least one human–animal pair were studied. Fecal samples were plated onto MacConkey and Hektoen agar and P. mirabilis PFGE analysis (NotI; Dice/UPGMA; 1.5% tolerance) was conducted for the households with multiple positive participants. Antimicrobial-resistance was tested according to CLSI. The fecal P. mirabilis pulse-types were compared with uropathogenic clinical strains (n = 183). Forty-nine P. mirabilis were isolated from eight households. The percentage of colonization in the dogs (44.4%, n = 8/18) was significantly higher (p = 0.0329) than in the humans (12.5%, n = 3/24). Three households had multiple colonized participants. One human–dog pair shared related P. mirabilis strains, which clustered with a clinical strain of animal origin (82.5%). One fecal P. mirabilis strain, from a dog, clustered with two human community-acquired clinical strains (80.9%, 88.9%). To our knowledge, this is the first report of dogs and humans living in close contact and sharing related P. mirabilis strains. The high frequency of colonization in the dogs underlines their possible role as P. mirabilis reservoirs for humans and other dogs.en
dc.description.statusPeer reviewed
dc.identifier.citationMarques , C , Belas , A , Menezes , J , da Silva , J M , Cavaco-Silva , P , Trigueiro , G , Gama , L T & Pomba , C 2022 , ' Human and Companion Animal Proteus mirabilis Sharing ' , Microbiology Research , vol. 13 , no. 1 , pp. 38-48 . https://doi.org/10.3390/microbiolres13010003
dc.identifier.doihttps://doi.org/10.3390/microbiolres13010003
dc.identifier.issn2036-7473
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85147481636&partnerID=8YFLogxK
dc.language.isoeng
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.relation.ispartofseriesvol.13, no.1, 38-48
dc.rightsopenAccess
dc.subjectProteus mirabilis
dc.subjectcompanion animals
dc.subjecthumans
dc.subjectreservoirs
dc.subjectsharing
dc.titleHuman and Companion Animal Proteus mirabilis Sharingen
dc.typearticle

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
microbiolres-13-00003-v2.pdf
Tamanho:
1.62 MB
Formato:
Adobe Portable Document Format
Descrição:
Artigo
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

CICANT - Artigos de Revistas Internacionais com Arbitragem Científica