Hipotiroidismo primário canino: descrição de 3 casos clínicos
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2022
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Este relatório de casos clínicos teve como objetivo a revisão bibliográfica de hipotiroidismo primário canino, bem como a descrição e discussão de três casos clínicos de cães diagnosticados com hipotiroidismo primário, acompanhados no Hospital House Vet. O hipotiroidismo e a doença endócrina mais comum em cães, ocorrendo maioritariamente devido a uma disfunção da tiroide (hipotiroidismo primário) e é caracterizado por uma diminuição das hormonas tiroideias. Os sinais clínicos mais frequentes são os metabólicos e dermatológicos. O diagnostico deve basear-se na anamnese, exame físico e exames sanguíneos, particularmente, a medição da concentração sérica de tiroxina total, tiroxina livre e tirotropina, e deve ser feito com cautela, uma vez que vários fatores podem alterar a função da tiroide. Para o tratamento e recomendada a administração de levotiroxina sódica oral, sendo essencial uma monitorização adequada do paciente. Os casos clínicos apresentaram-se a consulta com sinais clínicos sugestivos de hipotiroidismo, tendo-se procedido a realização de exames complementares de diagnostico e com base nos resultados concluiu-se que os pacientes apresentavam hipotiroidismo primário. Foi receitada levotiroxina sódica e posteriormente, os pacientes foram acompanhados para monitorização do hipotiroidismo. Todos os pacientes apresentaram uma boa resposta clínica ao tratamento instituído, tendo este melhorado a sua qualidade de vida. Palavras-chave: tiroidite linfocítica; hormonas tiroideias; síndrome do eutiroide doente; levotiroxina sódica; cães
This clinical case report is aimed to review the literature on canine primary hypothyroidism, as well as to describe and discuss three clinical cases diagnosed with primary hypothyroidism, followed at Hospital House Vet. Hypothyroidism is the most common endocrine disease in dogs, occurring generally due to a thyroid dysfunction (primary hypothyroidism) and is characterized by a decrease in thyroid hormones. The most frequent clinical signs are metabolic and dermatologic. The diagnosis should be based on the clinical history, physical exam and blood tests, especially the measure of the serum concentration of total thyroxine, free thyroxine and thyrotropin, and must be done carefully because many factors can alter thyroid function. For treatment it is recommended oral levothyroxine sodium and an adequate monitoring of the patient is crucial. The clinical cases presented to the medical appointment with clinical signs suggestive of hypothyroidism and complementary diagnostic tests were carried out, and based on the results, it was determined that the patients had primary hypothyroidism. It was prescribed levothyroxine sodium and later, the patients returned for monitoring of the hypothyroidism. All patients showed a good clinical response to the established treatment, which improved their quality of life. Keywords: lymphocytic thyroiditis; thyroid hormones; non-thyroidal illness syndrome; levothyroxine sodium; dogs
This clinical case report is aimed to review the literature on canine primary hypothyroidism, as well as to describe and discuss three clinical cases diagnosed with primary hypothyroidism, followed at Hospital House Vet. Hypothyroidism is the most common endocrine disease in dogs, occurring generally due to a thyroid dysfunction (primary hypothyroidism) and is characterized by a decrease in thyroid hormones. The most frequent clinical signs are metabolic and dermatologic. The diagnosis should be based on the clinical history, physical exam and blood tests, especially the measure of the serum concentration of total thyroxine, free thyroxine and thyrotropin, and must be done carefully because many factors can alter thyroid function. For treatment it is recommended oral levothyroxine sodium and an adequate monitoring of the patient is crucial. The clinical cases presented to the medical appointment with clinical signs suggestive of hypothyroidism and complementary diagnostic tests were carried out, and based on the results, it was determined that the patients had primary hypothyroidism. It was prescribed levothyroxine sodium and later, the patients returned for monitoring of the hypothyroidism. All patients showed a good clinical response to the established treatment, which improved their quality of life. Keywords: lymphocytic thyroiditis; thyroid hormones; non-thyroidal illness syndrome; levothyroxine sodium; dogs
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Orientação: Michelle Serafim
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VETERINÁRIA, MEDICINA VETERINÁRIA, VETERINARY MEDICINE, CANÍDEOS, CANIDS, CÃES, DOGS, CASOS CLÍNICOS, CASE REPORTS, HIPOTIROIDISMO, HYPOTHYROIDISM, MESTRADO INTEGRADO EM MEDICINA VETERINÁRIA, TIROIDITES, TIROIDITES, THYROIDITIS, HORMONAS TIROIDEIAS, THYROID HORMONES