Descrição da doença oncológica em Arctocephalus pusillus pusillus- estudo realizado num parque zoológico
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2016
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A casuística da doença oncológica relatada em pinípedes, tem sido crescente nos
últimos anos. No entanto, o desenvolvimento desta área continua com bastantes lacunas
devido à inexistência de estudos comparativos que estabeleçam padrões de incidência,
prevalência e patofisiologia em animais provenientes de ambiente selvagem e sob cuidados
humanos.
Com a presente dissertação procurámos identificar a doença oncológica em
Arctocephalus pusillus pusillus, descrevendo-a, e identificando diferentes tipos de neoplasias
nestes animais. A amostragem inicial deste estudo foi constituída por 10 animais (4 fêmeas e
6 machos), sendo diagnosticados 4 casos oncológicos, com recurso a procedimentos de
necrópsia e técnicas complementares de diagnóstico, como a histopatologia, testes
imunohistoquímicos e estudos bacteriológicos.
As neoplasias identificadas durante o processo de investigação foram: o melanoma
maligno, o carcinoma mamário, o adenoma da tiroide, o adenoma do córtex adrenal, o
sarcoma anaplásico, o carcinoma de células escamosas da nasofarínge e o condroma da
costela.
Este estudo permitiu-nos ainda identificar neoplasias que não estavam reportadas em
Arctocephalus pusillus pusillus e na família Otariidae, representando um impulso para a
investigação da presente doença em leões marinhos.
The number of reported cancer in pinnipeds has been increasing in recent years, however, knowledge in this area still presents many gaps due to the lack of comparative studies to establish patterns of incidence, prevalence and pathophysiology in wild animals and animals under human care. In this thesis we proposed to identify oncological disease in Arctocephalus pusillus pusillus (under human care), describ it, and identify different types of tumors in these animals. The initial sample for this study consisted of 10 animals (4 females/6 males), 4 of which diagnosed with oncological disease, having undergone necropsy and complementary diagnostic techniques procedures such as histopathology, immunohistochemistry tests and bacteriological studies. During the research process the following neoplasias were identified: malignant melanoma, mammarian carcinoma, thyroid adenoma, adrenal cortex adenoma, anaplatic sarcoma, nasopharyngeal squamous cell carcinoma and rib chondroma. In this study we were able to identify oncological process that had not yet been reported in the Arctocephalus pusillus pusillus species or in the Otariidae family, which represents a boost for the investigation of this disease in sea lions.
The number of reported cancer in pinnipeds has been increasing in recent years, however, knowledge in this area still presents many gaps due to the lack of comparative studies to establish patterns of incidence, prevalence and pathophysiology in wild animals and animals under human care. In this thesis we proposed to identify oncological disease in Arctocephalus pusillus pusillus (under human care), describ it, and identify different types of tumors in these animals. The initial sample for this study consisted of 10 animals (4 females/6 males), 4 of which diagnosed with oncological disease, having undergone necropsy and complementary diagnostic techniques procedures such as histopathology, immunohistochemistry tests and bacteriological studies. During the research process the following neoplasias were identified: malignant melanoma, mammarian carcinoma, thyroid adenoma, adrenal cortex adenoma, anaplatic sarcoma, nasopharyngeal squamous cell carcinoma and rib chondroma. In this study we were able to identify oncological process that had not yet been reported in the Arctocephalus pusillus pusillus species or in the Otariidae family, which represents a boost for the investigation of this disease in sea lions.
Descrição
Orientação : Pedro Faísca ; co-orientação : Carla Flanagan
Palavras-chave
MESTRADO INTEGRADO EM MEDICINA VETERINÁRIA, VETERINÁRIA, ONCOLOGIA VETERINÁRIA, NEOPLASIAS, MAMÍFEROS MARINHOS, VETERINARY ONCOLOGY, NEOPLASMS, MARINE MAMMALS, MEDICINA VETERINÁRIA, VETERINARY MEDICINE