Aplicações biomédicas da celulose bacteriana
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Data
2019
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Resumo
A preocupação e a importância da procura no desenvolvimento de novas soluções de fontes renováveis e o aumento da consciencialização ambiental, fez da celulose bacteriana uma excelente opção. Este material resulta do desenvolvimento da nanotecnologia e apresenta um processo de obtenção e purificação simples através de culturas bacterianas
A celulose bacteriana tem já aplicação em diversas áreas, como a indústria do papel, da alimentação, do som, da electrónica e digital, bem como no sector da saúde. Nesta dissertação procurou-se fazer uma abordagem das suas vantagens e diversas utilizações inovadoras com maior ênfase no sector biomédico.
Assim, serão descritas várias utilizações atuais e futuras aplicações para a celulose bacteriana, em áreas como a cosmética, o tratamento/regeneração de tecidos, ou a libertação controlada de fármacos.
A celulose bacteriana apresenta diversas vantagens em relação a celulose vegetal, sendo que é mais responsável ambientalmente tendo melhores características como pureza, alta permeabilidade para líquidos e gases, elevada capacidade de retenção de água, robustez mecânica e vastas possibilidades de compósitos com diferentes objectivos que são descritos na dissertação.
Apesar de todos os progressos feitos no desenvolvimento de novas terapêuticas e compostos/fármacos ainda existe espaço para crescimento devido à urgente necessidade de melhores estratégias para acelerar o tratamento, cicatrização e cura de diversas patologias mas aumentando também o conforto e comodidade para o utente.
The concern about, and the importance of, the demand for the development of new solutions of renewable sources together with the increase in environmental awareness meant that the study of bacterial cellulose was a compelling option. This material has arisen from the development of nanotechnology and it demonstrates the process of production and simple purification through bacterial cultures. Bacterial cellulose has already been applied in several commercial areas such as the paper, food, sound, electronics and digital industries, as well as in the health sector. In this dissertation I will analyse the advantages and several innovative uses with a focus on the biomedical sector. Accordingly, various current and future applications for bacterial cellulose will be examined and considered in areas such as cosmetics, tissue treatment, regeneration and controlled drugs release. Bacterial cellulose presents several advantages over vegetable cellulose as it is more environmentally responsible and has better attributes such as purity, high permeability to liquids and gases, high water retention capacity, mechanical robustness and vast possibilities of composites with different objectives. All of these factors will be examined and described in the dissertation. Despite all the progress made in the development of new therapeutics and compounds or drugs there is still room for growth due to the urgent need for better strategies to accelerate the treatment, healing and cure of various pathologies whilst at the same time increasing the comfort and convenience for the patient.
The concern about, and the importance of, the demand for the development of new solutions of renewable sources together with the increase in environmental awareness meant that the study of bacterial cellulose was a compelling option. This material has arisen from the development of nanotechnology and it demonstrates the process of production and simple purification through bacterial cultures. Bacterial cellulose has already been applied in several commercial areas such as the paper, food, sound, electronics and digital industries, as well as in the health sector. In this dissertation I will analyse the advantages and several innovative uses with a focus on the biomedical sector. Accordingly, various current and future applications for bacterial cellulose will be examined and considered in areas such as cosmetics, tissue treatment, regeneration and controlled drugs release. Bacterial cellulose presents several advantages over vegetable cellulose as it is more environmentally responsible and has better attributes such as purity, high permeability to liquids and gases, high water retention capacity, mechanical robustness and vast possibilities of composites with different objectives. All of these factors will be examined and described in the dissertation. Despite all the progress made in the development of new therapeutics and compounds or drugs there is still room for growth due to the urgent need for better strategies to accelerate the treatment, healing and cure of various pathologies whilst at the same time increasing the comfort and convenience for the patient.
Descrição
Orientação: Catarina Fialho Rosado
Palavras-chave
MESTRADO INTEGRADO EM CIÊNCIAS FARMACÊUTICAS, CIÊNCIAS FARMACÊUTICAS, BIOMEDICINA, SISTEMAS DE LIBERTAÇÃO DE MEDICAMENTOS, PHARMACEUTICAL SCIENCES, BIOMEDICINE, DRUG DELIVERY SYSTEMS, CELULOSE BACTERIANA, BACTERIAL CELLULOSE