Estudo preliminar da eficácia analgésica da administração de bupivacaína intraperitoneal em ovariohisterectomias eletivas em cadelas
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2021
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Com o passar do tempo, são cada vez mais notórios a preocupação e o interesse dos médicos veterinários para com a dor pós-operatória. A ovariohisterectomia eletiva é um exemplo de intervenção cirúrgica e de um procedimento de rotina em cães. Esta resulta num nível de dor aguda moderada, pelo que necessita de um tratamento analgésico adequado e eficaz.
Pretendeu-se com este trabalho avaliar a eficácia analgésica pós-operatória da administração de bupivacaína intraperitoneal em cadelas sujeitas a ovariohisterectomia eletiva.
Para tal, dez cadelas (n=10) que iriam ser sujeitas a ovariohisterectomia eletiva foram divididas aleatoriamente em dois grupos (n= 5 por grupo). O protocolo anestésico de ambos consistiu em dexmedetomidina e metadona como pré-medicação, propofol e/ou diazepam para a indução e isoflurano para a manutenção. A um dos grupos (GB) foi adicionada bupivacaína intraperitoneal a 0,25% numa dose de 3mg/kg, pelo que o outro grupo não recebeu nenhuma técnica de anestesia local (GM).
Para avaliar a dor pós-operatória foram usadas a Escala Visual Analógica, a Escala Visual Analógica Dinâmica e Interativa, a Forma Abreviada da Escala Composta de Dor de Glasgow e o Limiar Nocicetivo Mecânico.
Com o presente estudo não foi possível afirmar que esta técnica de anestesia local beneficia a analgesia pós-operatória em cadelas sujeitas a ovariohisterectomia eletiva, uma vez que não houve uma diferença estatisticamente significativa entre os dois grupos.
Serão necessários mais estudos com uma maior quantidade de indivíduos para avaliar a eficácia analgésica desta técnica de anestesia local em ovariohisterectomias eletivas de cadelas.
As time goes by, the concern and interest in post-operatory pain by veterinary doctors is ever more notorious. The elective ovariohysterectomy is an example of a surgical intervention and of a routine intervention in female dogs. It results in a moderate level of acute pain, hence needing an adequate and effective analgesic treatment. The intention of this work was to evaluate the post-operative analgesic efficacy of the administration of intraperitoneal bupivacaine in female dogs that underwent elective ovariohysterectomy. To achieve this, 10 female dogs (n=10) that would be undergoing elective OVH were randomly divided in two groups (n=5 per group). The anesthetic protocol of both groups consisted in dexmedetomidine and methadone as pre-medication, propofol and/or diazepam for inducing the anesthesia and isoflurane to maintain it. To one of the groups (GB) was added intraperitoneal bupivacaine at 0,25% in a dose of 3 mg/kg, whereas the other group (GM) did not receive any local anesthetic technique. To evaluate the post-operatory pain, the Visual Analog Scale, the Dynamic and Interactive Visual Analogue Scale, the Glasgow Composite Measure Pain Scale - Short Form and the Mechanical Nociceptive Threshold were used. With the current study it was not possible to confirm that this local anesthetic technique is beneficial to the post-operatory analgesia in female dogs subject to elective ovariohysterectomy, since there was no statistically significative difference between the two groups. More studies are needed, with a larger quantity of individuals, to evaluate the analgesic efficacy of this local anesthetic technique in female dogs’ elective ovariohysterectomy.
As time goes by, the concern and interest in post-operatory pain by veterinary doctors is ever more notorious. The elective ovariohysterectomy is an example of a surgical intervention and of a routine intervention in female dogs. It results in a moderate level of acute pain, hence needing an adequate and effective analgesic treatment. The intention of this work was to evaluate the post-operative analgesic efficacy of the administration of intraperitoneal bupivacaine in female dogs that underwent elective ovariohysterectomy. To achieve this, 10 female dogs (n=10) that would be undergoing elective OVH were randomly divided in two groups (n=5 per group). The anesthetic protocol of both groups consisted in dexmedetomidine and methadone as pre-medication, propofol and/or diazepam for inducing the anesthesia and isoflurane to maintain it. To one of the groups (GB) was added intraperitoneal bupivacaine at 0,25% in a dose of 3 mg/kg, whereas the other group (GM) did not receive any local anesthetic technique. To evaluate the post-operatory pain, the Visual Analog Scale, the Dynamic and Interactive Visual Analogue Scale, the Glasgow Composite Measure Pain Scale - Short Form and the Mechanical Nociceptive Threshold were used. With the current study it was not possible to confirm that this local anesthetic technique is beneficial to the post-operatory analgesia in female dogs subject to elective ovariohysterectomy, since there was no statistically significative difference between the two groups. More studies are needed, with a larger quantity of individuals, to evaluate the analgesic efficacy of this local anesthetic technique in female dogs’ elective ovariohysterectomy.
Descrição
Orientação: Lénio Bruno Martins Ribeiro ; coorientação: José Diogo Gonçalves dos Santos
Palavras-chave
MESTRADO INTEGRADO EM MEDICINA VETERINÁRIA, MEDICINA VETERINÁRIA, VETERINÁRIA, ANESTESIA VETERINÁRIA, OVARIOHISTERECTOMIA, DOR, VETERINARY MEDICINE, VETERINARY ANESTHESIA, OVARIOHYSTERECTOMY, PAIN, BUPIVACAÍNA, BUPIVACAINE